USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P34949 USC-OGP 2-DE database:  P34949 P34949 General information about the entry View entry in simple text format Entry name MPI_HUMAN Primary accession number P34949 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Mannose-6-phosphate isomerase; EC=5.3.1.8; AltName: Full=Phosphohexomutase; AltName: Full=Phosphomannose isomerase; Short=PMI;. Gene name Name=MPI Synonyms=PMI1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0410: pI=5.45; Mw=42538 Cross-references UniProtKB/Swiss-Prot P34949; MPI_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MPI_HUMAN Primary accession number P34949 Secondary accession number(s) A8K8K9 Q96AB0 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 182) Name and origin of the protein Description RecName: Full=Mannose-6-phosphate isomerase; EC=5.3.1.8; AltName: Full=Phosphohexomutase; AltName: Full=Phosphomannose isomerase; Short=PMI; Gene name Name=MPI Synonyms=PMI1 Encoded on Name=MPI; Synonyms=PMI1 Keywords Acetylation; Alternative splicing; Complete proteome; Congenital disorder of glycosylation; Cytoplasm; Direct protein sequencing; Disease mutation; Isomerase; Metal-binding; Phosphoprotein; Reference proteome; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X76057; CAA53657.1; -; mRNA EMBL AF227218; AAF37697.1; -; Genomic_DNA EMBL AF227216; AAF37697.1; JOINED; Genomic_DNA EMBL AF227217; AAF37697.1; JOINED; Genomic_DNA EMBL AK292374; BAF85063.1; -; mRNA EMBL CH471136; EAW99296.1; -; Genomic_DNA EMBL BC017351; AAH17351.1; -; mRNA EMBL BC046357; AAH46357.1; -; mRNA CCDS CCDS10272.1; -. [P34949-1]; . CCDS CCDS73757.1; -. [P34949-2]; . PIR S41122; S41122; . RefSeq NP_001276085.1; NM_001289156.1; . RefSeq NP_001276086.1; NM_001289157.1. [P34949-2]; . RefSeq NP_002426.1; NM_002435.2. [P34949-1]; . UniGene Hs.75694; -; . ProteinModelPortal P34949; -; . SMR P34949; -; . BioGrid 110491; 20; . IntAct P34949; 1; . STRING 9606.ENSP00000318318; -; . BindingDB P34949; -; . ChEMBL CHEMBL2758; -; . iPTMnet P34949; -; . PhosphoSitePlus P34949; -; . BioMuta MPI; -; . DMDM 462567; -; . OGP P34949; -; . EPD P34949; -; . MaxQB P34949; -; . PaxDb P34949; -; . PeptideAtlas P34949; -; . PRIDE P34949; -; . DNASU 4351; -; . Ensembl ENST00000323744; ENSP00000318192; ENSG00000178802. [P34949-2]; . Ensembl ENST00000352410; ENSP00000318318; ENSG00000178802. [P34949-1]; . GeneID 4351; -; . KEGG hsa:4351; -; . UCSC uc002azc.3; human. [P34949-1]; . CTD 4351; -; . DisGeNET 4351; -; . GeneCards MPI; -; . GeneReviews MPI; -; . HGNC HGNC:7216; MPI; . HPA HPA007200; -; . MalaCards MPI; -; . MIM 154550; gene; . MIM 602579; phenotype; . neXtProt NX_P34949; -; . OpenTargets ENSG00000178802; -; . Orphanet 79319; MPI-CDG; . PharmGKB PA30922; -; . eggNOG KOG2757; Eukaryota; . eggNOG COG1482; LUCA; . GeneTree ENSGT00390000016075; -; . HOGENOM HOG000241277; -; . HOVERGEN HBG000367; -; . InParanoid P34949; -; . KO K01809; -; . OMA QGEPWDT; -; . OrthoDB EOG091G078D; -; . PhylomeDB P34949; -; . TreeFam TF312831; -; . Reactome R-HSA-446205; Synthesis of GDP-mannose; . UniPathway UPA00126; UER00423; . GenomeRNAi 4351; -; . PRO PR:P34949; -; . Proteomes UP000005640; Chromosome 15; . Bgee ENSG00000178802; -; . CleanEx HS_MPI; -; . ExpressionAtlas P34949; baseline and differential; . Genevisible P34949; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0004476; F:mannose-6-phosphate isomerase activity; IBA:GO_Central; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0000032; P:cell wall mannoprotein biosynthetic process; IBA:GO_Central; . GO GO:0009298; P:GDP-mannose biosynthetic process; IBA:GO_Central; . GO GO:0061611; P:mannose to fructose-6-phosphate metabolic process; IEA:Ensembl; . GO GO:0006486; P:protein glycosylation; IBA:GO_Central; . Gene3D 2.60.120.10; -; 3; . InterPro IPR001250; Man6P_Isoase-1; . InterPro IPR016305; Mannose-6-P_Isomerase; . InterPro IPR018050; Pmannose_isomerase-type1_CS; . InterPro IPR014710; RmlC-like_jellyroll; . InterPro IPR011051; RmlC_Cupin; . PANTHER PTHR10309; PTHR10309; 1; . Pfam PF01238; PMI_typeI; 1; . PIRSF PIRSF001480; Mannose-6-phosphate_isomerase; 1; . PRINTS PR00714; MAN6PISMRASE; . SUPFAM SSF51182; SSF51182; 1; . TIGRFAMs TIGR00218; manA; 1; . PROSITE PS00965; PMI_I_1; 1; . PROSITE PS00966; PMI_I_2; 1; .

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